High dose atropine in organophosphorus poisoning.

نویسنده

  • H Kumar
چکیده

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منابع مشابه

Effect of Intensive Atropine Doses (Rapid Incremental Loading and Titration) for Management of Organophosphorus Pesticide Poisoning: a Case Series

Background:Acute poisoning with organophosphorus (OP) pesticides is a common method of suicide and entails considerable mortality in Bangladesh. The objective of this study was to evaluate the effects and outcomes of a protocol for treatment of OP poisoning that included titrated incremental atropine as loading dose and slow infusion for maintenance.  Methods:In this prospective descriptive cas...

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Continuous pralidoxime infusion versus repeated bolus injection to treat organophosphorus pesticide poisoning: a randomised controlled trial.

BACKGROUND The role of oximes for the treatment of organophosphorus pesticide poisoning has not been conclusively established. We aimed to assess the effectiveness of a constant pralidoxime infusion compared with repeated bolus doses to treat patients with moderately severe poisoning from organophosphorus pesticides. METHODS 200 patients were recruited to our single-centre, open randomised co...

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Clinical study of continuous micropump infusion of atropine and pralidoxime chloride for treatment of severe acute organophosphorus insecticide poisoning.

BACKGROUND Our study sought to assess the effectiveness of a constant micropump infusion of atropine and pralidoxime chloride compared with repeated-bolus doses in patients with severe acute organophosphorus insecticide poisoning (AOPP). METHODS A total of 60 patients with severe AOPP, defined as cholinergic crisis with respiratory failure or cerebral edema, were randomly divided into two gro...

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Oxidative stress and antioxidant status in acute organophosphorous pesticides poisoning cases of North Karnataka

This study was conducted to assess oxidative stress and antioxidant status of organophosphorus (OP) poisoning cases before and after therapy with atropine and pralidoxime of north Karnataka (India). For this study 30 male OP poisoning cases (study group) and 30 male normal healthy subjects (control group) having age range 17-40 years were taken. All organophosphorus poisoning cases were diagnos...

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[Efficacy of several oximes on organophosphorus poisoning].

Various organophosphorus compounds, particularly those with low acute toxicity levels, such as Fenitrothion (common name; Sumithion), Fenthion (common name; Baycid) and Pyridaphenthion (common name; Ofunack), are widely used as insecticides around the world. PAM (2-Pyridinum aldoxime methiodide), the specific antidote against Parathion, is not very effective against poisoning by these organopho...

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عنوان ژورنال:
  • Postgraduate medical journal

دوره 66 780  شماره 

صفحات  -

تاریخ انتشار 1990